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Top 5 Reasons Behind Failure Of IVF Treatment

Top 5 Reasons Behind Failure Of IVF Treatment

Globally, the average rate of success of IVF treatment is within 50%. Hence, around half of the people have failed ICF cycles and there is basically no scientific way to know the exact cause of IVF failure. IVF is basically a costly treatment procedure where there is no guarantee of success. Some of the common factors affecting the chances of failure are lab facilities, the way the procedure is performed, and the experience of the embryologist.

Even after choosing the best IVF clinic, if your IVF is failed, here are some of the common reasons which might be the problem. The development of an embryo in the womb is a complex process like several biological reasons.

1. Failed Embryo Implant

The IVF process is complex and it is not easy to know where the success rate is being affected. Failure of embryo implantation to the uterus is one of the most common causes. It could take place either because of problems with the uterus or problems with embryos. But it is not easy to figure out what caused the failure of your case. A lot of experts believe the arrest of embryos causes failure in implantation in around 90% of cases. Most of the embryos die within 5 days. Even the good ones die in some time after transplantation, which survives the initial days and seems healthy. Chromosomal or genetic defects can also cause weakness of embryo.

2. Age of Mother and Ovarian Response

The health of the uterus, age of the woman and how her body responds to medications are the factors affecting IVF success. Ovary usually releases one egg per month, i.e. from the collection of the egg which is fixed at birth which declines by the mid-30s. Medications are provided to produce more eggs before the IVF cycle. If you have lower eggs already or you have increased FSH levels, your body may not be able to respond to IVF medications well, which is definitely not a good sign.

3. Quality of Eggs

At 50% or above, the rates of embryo implantation are higher in women by mid-30s, in comparison to up to 12% in women above 40 years. Older women will often wonder what happened to their uterus or why embryos are not transplanted. Some women also hire surrogate but science doesn’t accept it. Using IVF has higher odds to bring success in most cases when the uterus doesn’t have common problems. Even transferring your eggs to the uterus of the surrogate will not give better results if egg quality is not good enough.

4. Sperm Quality

Sperm should be motile, healthy, and of good quality to fertilize the female egg. Both eggs and sperm have receptors on the surface which enable interaction. Enzymes are released off the sperm head when it happens. It creates hope in outer membranes so it can get into the egg.

5. Chromosomal Causes

Chromosomal irregularities are some of the common causes of IVF failure. According to several studies, chromosomal irregularities in human embryos start rising dramatically after the mid-30s. Older eggs don’t have proper spindle apparatus which can line up the pairs of chromosomes.

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