Sub-Endometrial PRP

How PRP Works in IVF Recurrent Failure Cases

The uterus serves as an essential condition for embryonic implantation to succeed. Embryos of the best quality require a receptive and healthy endometrium for successful implantation. Here’s how PRP helps:

Promotes Endometrial Growth

The endometrial lining achieves better health and thickness through the growth factors VEGF, PDGF, and TGF-β, which promote cellular proliferation and angiogenesis.

Improves Endometrial Receptivity

PRP rejuvenates the endometrial tissue, leading to higher expression levels of embryo implantation molecules such as integrins and LIF (Leukaemia Inhibitory Factor).

Reduces Inflammation

Uterine chronic inflammation functions as a secret reason behind numerous treatment failures in menstrual cycles. Anti-inflammatory cytokines present in PRP help restore proper endometrial conditions.

Enhances Blood Flow

PRP contains growth factors that drive fresh blood vessel development, enhancing the delivery of oxygen and nutrients to the uterine lining.

PRP Procedure at Mannat Fertility Centre

Mannat Fertility Centre implements an evidence-based protocol and highly standardised sterile procedure to produce PRP treatments, which includes  the following steps.

Step-by-Step Process:

• Blood Collection: A medical professional obtains a small amount of sterile blood through a blood sample.
• PRP Preparation: The platelets can be isolated from blood through centrifugation to generate the PRP concentrate.
• Ultrasound-Guided Injection: The medical staff guides PRP injections through a thin  sterile needle into the sub-endometrial space or into the uterus using a thin catheter(most commonly used and simple) with the visual assistance of a transvaginal ultrasound.
• Monitoring: Doctors evaluate endometrial lining thickness and response through monitoring during 3- to 7-day.
• Embryo Transfer: The planned frozen or fresh embryo transfer procedure occurs after the endometrium reaches the desired thickness and vascularity.

The treatment uses autologous blood components from your body, delivering both safety and natural effects with minimal adverse reactions.

Who Can Benefit from Subendometrial PRP?

The therapy benefits women who have experienced the following conditions:

• Multiple failed In Vitro fertilisation attempts have occurred, although the medical team transferred excellent embryo samples.
• Thin endometrium (<7mm) resistant to hormonal support
• Endometrial scarring or fibrosis
• Chronic endometritis
• History of repeated biochemical pregnancies or early miscarriages

Why Choose Mannat Fertility Centre for PRP Treatment?

Scientific Precision, Personalised Care

The PRP treatment delivery and monitoring process involves experienced doctors who use advanced imaging technology and lab protocols under the leadership of experienced doctors.

Customised IVF Protocols

The IVF plan incorporates PRP according to hormonal test results, endometrial imaging and past fertility cycle results.

Ethical & Transparent Approach

We believe in informed choices. The staff will provide you with detailed information about the procedure, its expected outcomes, and its advantages.

Natural & Minimally Invasive

Your body’s healing process remains untouched since PRP relies exclusively on natural processes to deliver maximum results.

Higher Success Rates

The application of sub-endometrial PRP therapy led to increased implantation and pregnancy success among our preliminary patient groups.

Affordable Cost

The cost of PRP Treatment in Bangalore typically ranges between ₹15,000 to ₹25,000, depending on the tests included and the clinic’s expertise.

Clinical Evidence Supporting PRP

Medical research has presented desirable developments from multiple recent studies and trials.

• Research shows that women with a thin endometrium (less than 7 mm) experienced their lining becoming at least 7.5 mm thick after receiving PRP therapy over a 48 to 72-hour period.
• A review of multiple clinical trials demonstrated that PRP treatment groups achieved pregnancy and implantation rates that were twofold higher than those of control groups.
• The safety profile of PRP therapy for reproductive medicine became more evident because no adverse effects occurred during treatment.

Precautions & Side Effects

The procedure of sub-endometrial PRP treatment comes with safety yet requires execution only by qualified experts within sanitary facilities. Potential, though rare, concerns include:

• Mild cramping or spotting post-procedure
• Infection (rare due to autologous origin and sterile procedure)
• Your blood used in the treatment has no reported allergic reactions because it is your own biological substance.

Final Thoughts

Subendometrial PRP injection shows excellent potential to help reproductive medicine treat women who have experienced multiple unsuccessful IVF attempts. Mannat Fertility Centre joins advanced medical innovation with compassionate care and services to guide you confidently on your path to becoming a parent.

People who have experienced IVF failure or have weak endometrial lining should contact our centre. You might just be one PRP shot away from success.

You can reach Mannat Fertility Centre present or schedule your appointment through their online booking system. Let’s explore your best options—together.