The multiple reasons behind recurrent pregnancy loss exist as a combination of various factors. Recurrent pregnancy loss develops from multiple potential reasons which include:
Genetic Factors
The development of embryos with chromosomal abnormalities occurs when either partner carries genetic abnormalities leading to miscarriage. The abnormalities develop through inheritance from parents or they appear randomly during the fertilization process.
Anatomical Issues
The implantation and growth of an embryo becomes difficult when a septate uterus (a partition dividing the uterine cavity) or fibroids exist within the physical structure of the uterus. Medical treatments such as surgery alongside other interventions address these conditions effectively.
Hormonal Imbalances
The pregnancy process gets disrupted by hormonal disorders including thyroid imbalances and polycystic ovary syndrome (PCOS). The implantation process and early fetal development may be disrupted when a woman has insulin resistance, low progesterone levels, or luteal phase defects.
Autoimmune Disorders
Pregnancy loss becomes more likely when a person has antiphospholipid syndrome (APS) or lupus because these autoimmune disorders cause the immune system to attack body tissues. The use of immune-regulating medications helps to enhance pregnancy results in these situations.
Blood Clotting Disorders
The inheritance of Factor V Leiden or protein S deficiency causes blood clotting disorders that result in reduced placental blood flow and increase the risk of miscarriage.
Age-Related Factors
Elderly women above 35 experience declining egg quality and quantity leading to embryo chromosomal irregularities that raise the possibility of miscarriage.
Lifestyle Factors
Smoking along with excessive alcohol consumption and having either overweight or underweight conditions raises the chances of experiencing recurrent pregnancy loss. The reproductive health and blood flow along with hormonal balance face negative impacts from these elements.